Which Big 12 football teams have the best chances of winning their games on the college football Week 2 schedule?

ESPN Analytics has revealed its matchup predictor numbers for the games in the conference this week, and they offer some interesting win probabilities.

Take a look at the site's picks for this week's Big 12 Conference games, including Arizona State at Texas A&M, Missouri at Kansas, Oregon at Oklahoma State and Arizona at BYU on Saturday, Sept. 12.

Some of the site's predictions differ from college football Week 2 odds and other college football Week 2 picks for college football Week 2 games. How correct will the analytics be this week?

All times MST.

Big 12 football Week 2 picks: Missouri vs Kansas | Oregon vs Oklahoma State | Arizona State vs Texas A&M | Washington State vs Kansas State | Arizona vs BYU | UCF vs Pittsburgh | Texas Tech vs Oregon State | Iowa State vs Iowa | Arkansas vs Utah | Big 12 score predictions

Watch select Big 12 football games on FUBO (free trial)

Big 12 football Week 2 prediction: Friday, Sept. 11

  • Missouri at Kansas, 5 p.m., FOX (stream with FUBO)

Missouri has a 63.2% chance to defeat Kansas on Friday.

The site gives the Jayhawks a 36.8% shot at winning the college football Week 2 game.

College football Week 2 picks: Oklahoma vs Michigan | Penn State vs Temple | Western Kentucky vs Georgia | Alabama vs Kentucky | Utah State vs Washington | Tennessee vs Georgia Tech | Ohio State vs Texas | Louisiana Tech vs LSU | Louisiana vs USC

Big 12 football Week 2 predictions: Saturday, Sept. 12

  • Oregon at Oklahoma State, 9 a.m., ESPN (stream with FUBO)

Oregon has a 93% chance to defeat Oklahoma State on Saturday.

The site gives the Cowboys a 7% shot at winning the college football Week 2 game.

  • Arizona State at Texas A&M, 9 a.m., ABC (stream with FUBO)

Texas A&M has an 88.6% chance to defeat Arizona State on Saturday.

The site gives the Sun Devils an 11.4% shot at winning the college football Week 2 game.

Betting: Arizona State vs Texas A&M odds for college football Week 2 game

  • Washington State at Kansas State, 9 a.m., TNT (stream with Sling)

Kansas State has an 88.3% chance to defeat Washington State on Saturday.

The site gives the Cougars an 11.7% shot at winning the Week 2 game.

  • UT Martin at West Virginia, 10 a.m., ESPN+ (stream with ESPN+)

West Virginia has a 97.1% chance to defeat UT Martin on Saturday.

The site gives the Skyhawks a 2.9% shot at winning the college football Week 2 game.

  • Arizona at BYU 12:30 p.m., FOX(stream with FUBO)

BYU has a 76.8% chance to defeat Arizona on Saturday.

The site gives the Wildcats a 23.2% shot at winning the college football Week 2 game.

Betting: Arizona vs BYU odds for college football Week 2 game

  • Weber State at Colorado, 12:30 p.m., ESPN+ (stream with ESPN+)

Colorado has a 98% chance to defeat Weber State on Saturday.

The site gives the Wildcats a 2% shot at winning the college football Week 2 game.

  • UCF at Pittsburgh, 12:30 p.m., ESPN2 (stream with FUBO)

Pittsburgh has a 75.4% chance to defeat UCF on Saturday.

The site gives the Knights a 24.6% shot at winning the college football Week 2 game.

  • Southern at Houston, 4 p.m., ESPN+ (stream with ESPN+)

Houston has a 99% chance to defeat Southern on Saturday.

The site gives the Jaguars a 1% shot at winning the college football Week 2 game.

Big 12 football Week 2 schedule: TV channels, how to watch games

  • Western Carolina at Cincinnati, 4 p.m., ESPN+ (stream with ESPN+)

Cincinnati has a 97.4% chance to defeat Western Carolina on Saturday.

The site gives the Catamounts a 2.6% shot at winning the college football Week 2 game.

  • Texas Tech at Oregon State, 4:30 p.m., CBS (stream with FUBO)

Texas Tech has a 94% chance to defeat Oregon State on Saturday.

The site gives the Beavers a 6% shot of winning the college football Week 2 game.

  • Iowa State at Iowa, 4:30 p.m., NBC (stream with Peacock)

Iowa has an 84.5% chance to defeat Iowa State on Saturday.

The site gives the Cyclones a 15.4% shot at winning the college football Week 2 game.

Big 12 football Week 2 odds: Point spreads, moneylines, over/unders

Iowa State head coach Jimmy Rogers talks to players during the fourth quarter against Southeast Missouri in the week one NCAA football at Jack Trice Stadium on Sept. 5, 2026, in Ames, Iowa.
  • Prairie View A&M at Baylor, 5 p.m., ESPN+ (stream with ESPN+)

Baylor has a 98.4% chance to defeat Prairie View A&M on Saturday.

The site gives the Panthers a 1.6% shot at winning the college football Week 2 game.

  • Grambling at TCU, 5 p.m., ESPN+ (stream with ESPN+)

TCU has a 99% chance to defeat Grambling on Saturday.

The site gives the Tigers a 1% shot at winning the college football Week 2 game.

  • Arkansas at Utah, 7:15 p.m., ESPN (stream with FUBO)

Utah has an 81.8% chance to defeat Arkansas on Saturday.

The site gives the Razorbacks an 18.2% shot at winning the college football Week 2 game.

Big 12 football Week 2 picks: Predictions for game scores this week

Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

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This article originally appeared on Arizona Republic: Big 12 football predictions, picks, win probabilities for Week 2 games

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Source: Yahoo Sports