STILLWATER — Even for elite college football teams, Boone Pickens Stadium is a tough place to win in.

In recent memory, the Oklahoma State Cowboys have held their own at home against top-10 ranked teams. Since 2010, OSU has hosted 11 top-10 teams and has a 7-4 record in the games. OSU hasn’t lost to a top-10 team at home since 2019 against No. 7 Oklahoma.

Saturday, the Cowboys will be tested against No. 6 Oregon at 11 a.m. on ESPN. Oregon’s only two losses last season came against Indiana, the eventual national champion.

The Ducks enter the game as a 22.5-point favorite against the Cowboys and first-year coach Eric Morris, who is making his Boone Pickens Stadium debut.

Follow for live updates from the Cowboys vs. Ducks.

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Watch OSU vs. Oregon football live with Fubo

Oklahoma State vs Oregon score updates

More: Oklahoma State football schedule: Dates, times, TV channels for 2026 OSU Cowboys

Oregon football scouting report for Week 2 vs. Oklahoma State

11:15 AM ET, September 12 2026, Ben Hutchens

2026 Record: 1-0, 0-0 Big Ten

Best player: Senior quarterback Dante Moore is a top-five Heisman Trophy favorite and potentially the top player at his position in the NFL Draft. He started his campaign strong in Oregon’s opener against Boise State throwing for 378 yards and three touchdowns on 75.7% completion accuracy. Moore is an elite arm-talent. He led college football last season with 15 touchdown passes traveling at least 20 yards downfield. He lit the Cowboys up for 266 yards and three touchdowns last year.

The case for Oregon: The Ducks have lost three games over the past two years: Twice last season to eventual national champion Indiana and once in 2024 to eventual national champion Ohio State. The Cowboys did not look like national championship contenders in Week 1. Skilled receivers Dakorien Moore and Jeremiah McClellan will win matchups against OSU corners and Oregon will generate chunk plays in the passing game. The Cowboys offense, searching for a new left tackle following Jacob Sexton's injury and a backup running back behind Caleb Hawkins, won’t be able to score enough points to keep up.

The case for OSU: Oregon looked beatable against Boise State. The Ducks trailed 17-7 just before halftime and hurt themselves, committing 10 penalties for 90 yards. Hawkins was solid against Tulsa, rushing for 4.4 yards per carry. OSU’s offense was at it's best with Hawkins carrying the football. If the Cowboys can run the ball and control the clock they can keep Oregon’s dynamic offense on the sideline.

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11:01 AM ET, September 12 2026

Take a stroll down memory lane with a look at our photo gallery of legendary OSU football wide receiver Dez Bryant.

More: Oklahoma State football schedule: Dates, times, TV channels for 2026 OSU Cowboys

Oklahoma State football schedule 2026

10:45 AM ET, September 12 2026

All times are Central

  • Saturday, Sept. 5: Tulsa 24, OSU 10 | Box score
  • Saturday, Sept. 12: vs. Oregon, 11 a.m., ESPN
  • Saturday, Sept. 19: vs. Murray State, 6 p.m., ESPN+
  • Saturday, Sept. 26: at West Virginia, Fox or FS1
  • Saturday, Oct. 10: vs. UCF, TBA
  • Saturday, Oct. 17: at Houston, TBA
  • Saturday, Oct. 24: vs. Colorado, TBA
  • Saturday, Oct. 31: at Iowa State, TBA
  • Saturday, Nov. 7: at Kansas State, TBA
  • Saturday, Nov. 14: vs. Texas Tech, TBA
  • Saturday, Nov. 21: at Arizona State, TBA
  • Saturday, Nov. 28: vs. Kansas, TBA

Oregon football schedule 2026

10:30 AM ET, September 12 2026

All times are Central

  • Saturday, Sept. 5: Oregon 34, Boise State 27
  • Saturday, Sept. 12: at Oklahoma State, 11 a.m., ESPN
  • Friday, Sept. 18: vs. Portland State, 9:30 p.m. (BTN)
  • Saturday, Sept. 26: at USC, TBA
  • Saturday, Oct. 10: vs. UCLA, TBA
  • Saturday, Oct. 17: vs. Nebraska, TBA
  • Saturday, Oct. 24: at Illinois, TBA
  • Saturday, Oct. 31: vs. Northwestern, TBA
  • Saturday, Nov. 7: at Ohio State, TBA
  • Saturday, Nov. 14: vs. Michigan, TBA
  • Friday, Nov. 20: at Michigan State, 7 p.m. (Fox)
  • Saturday, Nov. 28: vs. Washington, TBA

3 things to watch, 1 prediction for OSU football game vs Oregon in home opener

10:15 AM ET, September 12 2026

The Oklahoman's Jenni Carlson breaks down the Oklahoma State vs. Oregon Week 2 college football game. Can the Cowboys upset the Ducks for the first win of the Eric Morris era?

Oklahoma State vs Oregon predictions, picks, odds

10:01 AM ET, September 12 2026, Ben Hutchens

Odds courtesy of BetMGM as of Friday, Sept. 11:

  • Spread: ORE (-23)
  • Over/under: 55.5
  • Moneyline: ORE -2000 | OSU +1150

Prediction: Oregon 44, OSU 18

Oregon quarterback Dante Moore has a big passing day as the Ducks comfortably defeat Cowboys for second straight year. Against strong Oregon defense and without tackle Jacob Sexton, OSU offense still looks like its coming together. —Ben Hutchens, The Oklahoman

More: How can Oklahoma State slow Oregon football QB Dante Moore's passing game?

What channel is Oklahoma State vs Oregon on today? Where to watch Cowboys-Ducks game

09:45 AM ET, September 12 2026

  • TV channel: ESPN
  • Streaming: Fubo (free trial)

Oklahoma State vs Oregon will air live on ESPN, with streaming options on Fubo, which offers a free trial.

MUSSATTO: What a 'win' for Oklahoma State football vs. Oregon would look like

What time does Oklahoma State football play Saturday? OSU vs Oregon game time

09:30 AM ET, September 12 2026

  • Time: 11 a.m. CT
  • Date: Saturday, Sept. 12
  • Location: Boone Pickens Stadium in Stillwater

The Cowboys-Ducks game is set for a 11 a.m. CT kickoff on Saturday, Sept. 12, from Boone Pickens Stadium in Stillwater.

More: Why an Oklahoma State student is punishing himself for every football loss

Big 12 football schedule for Week 2 of 2026 college football season

09:15 AM ET, September 12 2026

All times CT

  • Missouri 38, Kansas 21
  • Arizona State at Texas A&M, 11 a.m. CT Saturday (ABC)
  • Washington State at Kansas State, 11 a.m. CT Saturday (TNT)
  • Oregon at Oklahoma State, 11 a.m. CT Saturday (ESPN)
  • UT Martin at West Virginia, noon CT Saturday (ESPN+)
  • Weber State at Colorado, 2:30 p.m. CT Saturday (ESPN+)
  • Arizona at BYU, 2:30 p.m. CT Saturday (Fox)
  • UCF at Pittsburgh, 2:30 p.m. CT Saturday (ESPN2)
  • Southern at Houston, 6 p.m. CT Saturday (ESPN+)
  • Western Carolina at Cincinnati, 6 p.m. CT Saturday (ESPN+)
  • Texas Tech at Oregon State, 6:30 p.m. CT Saturday (CBS)
  • Iowa State at Iowa, 6:30 p.m. CT Saturday (NBC)
  • Prairie View A&M at Baylor, 7 p.m. CT Saturday (ESPN+)
  • Grambling State at TCU, 7 p.m. CT Saturday (ESPN+)
  • Arkansas at Utah, 9:15 p.m. CT Saturday (ESPN)

This article originally appeared on Oklahoman: Oklahoma State vs Oregon football live updates: Start time, TV channel for Week 2 game

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Source: Yahoo Sports