Week 11 in the Big 12 kicks off Friday as multiple teams look to secure bowl eligibility and keep their chances alive, including Colorado, which faces Houston.

But Saturday brings more interesting games. Cincinnati and Iowa State will be a crucial matchup for both teams as they try to become bowl-eligible, as well as Kansas State's battle against TCU and Arizona State's game against UCF. There is also a pair of ranked matchups: Utah vs. Arizona and Texas Tech vs. Oklahoma State.

Big 12 Game of the Week

Nov 7, 2026; Salt Lake City, Utah, USA; Utah Utes wide receiver Braden Pegan (7) reacts with wide receiver Creed Whittemore (2) after scoring a touchdown during the first quarter against the Brigham Young Cougars at Rice-Eccles Stadium. Mandatory Credit: Rob Gray-Imagn Images

Best Game of the Week: Utah vs. Arizona

Realistically, this is probably Utah's last chance to lose a regular-season game as they try to secure their spot in the Big 12 Championship game and cement themselves as one of the best teams in college football. Arizona is a formidable opponent, especially with their quarterback Noah Fifita and wide receiver Isaiah Mizell. This could be a high-scoring shootout and a game all Big 12 fans should tune in to.

Big 12 Upset to Watch

Nov 7, 2026; Manhattan, Kansas, USA; Oklahoma State Cowboys wide receivers Miles Coleman (1) and Justin Bowick (0) celebrate a touchdown during the second quarter against the Kansas State Wildcats at Bill Snyder Family Football Stadium. Mandatory Credit: Scott Sewell-Imagn Images

Potential Upset: Texas Tech vs. Oklahoma State

When the season started, it would have been hard to imagine Oklahoma State being favored in this game. However, with how well quarterback Drew Mestemaker has played and the litany of offensive injuries for the Red Raiders, the Cowboys are now favored to win their fifth conference game. This has serious playoff implications, as Texas Tech could lose their spot in the final Big 12 Championship with a loss. With the stakes that high, the Red Raiders will put up a strong fight, which should make it very interesting to watch.

Other Big 12 action

Oct 31, 2026; Provo, Utah, USA; Brigham Young Cougars cornerback Therrian Alexander (1) breaks up a pass intended for Arizona State Sun Devils wide receiver Reed Harris (3) during the first half at LaVell Edwards Stadium. Mandatory Credit: Rob Gray-Imagn Images

Among other Big 12 action, Houston is taking on Colorado on Friday. With a loss, the Buffaloes would not be bowl-eligible this season. On Saturday, Cincinnati will look to secure bowl eligibility, while Iowa State will look to get one game closer. Kansas State's game against TCU will also be crucial for bowl eligibility purposes as both teams are sitting at 4-5.

When Arizona State takes on UCF, the winner will become bowl eligible since both teams currently have five wins. West Virginia will also be looking to secure bowl eligibility when they take on Kansas. The Jayhawks need this win to keep their bowl chances alive. BYU will also look to stay in the playoff picture when they take on Baylor.

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This article originally appeared on Buffaloes Wire: Big 12 football Week 11 schedule preview: Top games, upset pick

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